USPTO Patents Application 10055569

Applicant: Gangolli et at
U.S.S.N. 10/055,569

Amendments to the Claims:

This listing of claims will replace all prior versions, and listings, of claims in the
application:

1.-4. (canceled)

5. (previously presented) An isolated nucleic acid molecule comprising a nucleic acid
sequence encoding a polypeptide comprising an amino acid sequence SEQ ID NO; 20.

6. (previously presented) The nucleic acid molecule of claim 5, wherein the nucleic acid
molecule comprises the nucleotide sequence SEQ ID NO: 19.

7. (previously presented) An isolated nucleic acid molecule comprising a nucleic acid
sequence which encodes a polypeptide comprising amino acids 24-579 of SEQ ID NO: 20.

8. (cancelled)

9. (previously presented) The nucleic acid molecule of claim 5 consisting of SEQ ID
NO: 19.

10. - 11. (canceled)

12. (previously presented) A vector comprising the nucleic acid molecule of claim 5.

13. (original) The vector of claim 12, further comprising a promoter operably-linked to said
nucleic acid molecule.

14. (currently amended) A cell comprising the vector of claim 12 , wherein said cell is
transformed with said vector.

Applicant: Gangolli et ah
U.S.S.N. 10/055,569

15.-29. (canceled)

30. (previously presented) A composition comprising the nucleic acid molecule of claim 5
and a pharmaceutically-acceptable carrier.

31. -32. (canceled)

33. (previously presented) A kit comprising in one or more containers, the composition of
claim 30.

34. - 42. (canceled)

43. (currently amended) The A variant of the nucleic acid molecule of claim 4 2 claim 5,
wherein the nucleotide at position 227 is T or C.

44. (currently amended) The A variant of the nucleic acid molecule of claim 42 claim 5,
wherein the nucleotide at position 482 is T or C.

45. (currently amended) The A variant of the nucleic acid molecule of claim 42 claim 5,
wherein the nucleotide at position 523 is A or G.

46. (currently amended) T-The A variant of the nucleic acid molecule of claim 42 claim 5,
wherein the nucleotide at position 548 is G or A.

47. (currently amended) The A variant of the nucleic acid molecule of claim 4 2 claim 5,
wherein the nucleotide at position 573 is G or A.

48. (currently amended) The nucleic acid molecule of claim 42 wherein the nucleotide at
position 684 is T or C.

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